Both sides will feature players making landmark appearances in the latest, and last (or at least it is for now) inter-city derby of the season(s).
Blair Kinghorn will rack up a century of caps for his hometown club after missing last week’s barnstorming affair on compassionate grounds, and in doing so will become the youngest Edinburgh player to reach the milestone.
Meanwhile, joining a slightly more exclusive club in Glasgow will be Rob Harley, who becomes the first Warrior to reach 250 professional club caps, and only the second in Scotland behind Edinburgh’s legendary Allan “Chunk” Jacobsen.
On the other ends of the appearance scale, Charlie Savala makes his first home start for Edinburgh, while in the front-row for Glasgow, Tom Lambert will make his first start at loosehead coming up against the fearsome scrummaging power of WP Nel.
With none of the Lions class of 2021 on show this weekend, the last Scot to make a Test appearance in Lion Red, Richie Gray, will represent, as he partners Harley in a Glasgow engine room with a combined cap total of 311, compared to Edinburgh pair Jamie Hodgson and Marshall Sykes’ twenty-six.
In the Glasgow backs, Ali Price is rested with George Horne coming in, Adam Hastings replaces Cole Forbes at full-back, but Kyle Steyn and Ratu Tagive continue on the wings – although seemingly switching from last week going by jersey number – and Nick Grigg and Stafford McDowall partner up again in midfield.
Amongst the Edinburgh back division, Kinghorn’s inclusion at full-back sees Damien Hoyland move to the right-wing, with Eroni Sau crossing over to the left in place of Duhan van der Merwe who picked up a knock last week. Chris Dean and James Johnstone will be reunited in the centres, with George Taylor moving onto the bench and Mark Bennett suspended.
Edinburgh: Blair Kinghorn, Damien Hoyland, James Johnstone, Chris Dean, Eroni Sau, Charlie Savala,
Henry Pyrgos; Pierre Schoeman, Stuart McInally, WP Nel, Marshall Sykes, Jamie Hodgson, Mesu Kunavula,
Luke Crosbie, Vilame Mata
Replacements: Mike Willemse, Boan Venter, Lee-Roy Atalifo, Ally Miller, Connor Boyle, Charlie Shiel, Jack Blain,
Glasgow Warriors: Adam Hastings, Kyle Steyn, Nick Grigg, Stafford McDowall, Ratu Tagive, Ross Thompson, George Horne; Tom Lambert, George Turner, Enrique Pieretto, Rob Harley, Richie Gray, Ryan Wilson,
Rory Darge, Matt Fagerson
Replacements: Grant Stewart, Dylan Evans, D’arcy Rae, Kiran McDonald, Thomas Gordon, Jamie Dobie,
Pete Horne, Lee Jones