New signing Callum Gibbins will make his debut in Dave Rennie’s first home game at Scotstoun, with the New Zealander part of a powerful back row unit alongside captain Ryan Wilson and Adam Ashe.
Part-time Lion and full-time party animal Finn Russell returns to the team as Pete Horne moves into the centre for Sam Johnson in a similar looking backline to the one that beat Connacht in the rain. Despite the two tries scored, this time they will be hoping for better handling conditions, the other change being Rory Hughes swapping out for Lelia Masaga.
Up front the only pack change is Gibbins who comes in for Matt Smith, but on the bench there are a few fresh faces including Pat MacArthur, Darcy Rae, big Brian and Nick Grigg. Adam Hastings sits this one out with a gash in his leg picked up last weekend.
Overall Rennie seems to be sticking to a core team while still figuring out who those ideal second or third string players will be once the selection troubles bite in the Autumn.
Glasgow will take on an Ospreys side with plenty of experience led by Justin Tipuric, but still some way short of their top side and the WarriorNation will surely be baying for a win at the top of their considerable voices.
Glasgow Warriors: Ruaridh Jackson, Lee Jones, Alex Dunbar, Pete Horne, Rory Hughes, Finn Russell, Ali Price; Jamie Bhatti, George Turner, Zander Fagerson, Tim Swinson, S Scott Cummings, Ryan Wilson (capt), Callum Gibbins, Adam Ashe
Replacements: Pat MacArthur, Oli Kebble, Darcy Rae, Brian Alainu’uese, Matt Fagerson, Henry Pyrgos, Nick Grigg, Leonardo Sarto.
Ospreys: Dan Evans; Keelan Giles, Kieron Fonotia, Cory Allen, Jeff Hassler; Sam Davies, Tom Habberfield; Paul James, Sam Parry, Ma’afu Fia, Bradley Davies, Lloyd Ashley, Olly Cracknell, Justin Tipuric (capt), James King.
Replacements: Scott Otten, Nicky Smith, Rhodri Jones, Adam Beard, Guy Mercer, Reuben Morgan-Williams, James Hook, Jay Baker.
Referee: Marius Mitrea, (Italy)
Live on Sky Sports Arena (kick-off 3.15pm).